Particle Works carefully designs and builds innovative, pioneering technology for the whole customer journey, from protocol development and discovery to manufacturing and scale up. The discovery phase often requires high throughput screening of different potential mRNA molecules and lipid formulations to establish the ideal properties and responses.
The Automated Library Synthesis (ALiS) System is the first part of the customer journey, built for this purpose, and is aimed for research and development facilities where scientists are looking for the next best drug formulation or next best vaccine. Customers don’t have to worry about small batches, tiny volumes of fluids, glassware, and trying not to waste anything. Our high throughput screening ALiS System is equipped with fluid handlers that can automate aspiration from well plates, and advanced pumps to push those through the system before mixing at the junction in our carefully designed chips.
Once the user finds the size, shape and structure that works effectively, the process is optimized for reliable, reproducible and higher throughput particle production. The Automated Nanoparticle (ANP) System is next in the customer journey, and is aimed at protocol development for performing a series of automated experiments from a single pair of reagents. Lots of different experiments can be conducted in just one injection, but each of those experiments will ultimately use the same reagent.
The ANP Pilot is the GMP compliant of our ANP system, which can be used for production of particles for clinical trials and initial scale up manufacturing. The higher throughput platform, Titan, is the final step of the customer journey, allowing high volume manufacture in GMP facilities.
